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FORMULATION DEVELOPMENT

Avrio’s cGMP facility incorporates state-of-the art equipment and a dynamic team of experienced formulation scientists with a successful track record to provide clients cutting-edge solutions and responsive customer care.

Our formulation team consists of highly skilled, experienced scientists with a comprehensive understanding of all facets of the drug development process and dosage forms with a stellar track record of pre-formulation, formulation development, technology transfer, and manufacturing.

In-depth Pre-formulation Services

  • Solubility and pH-rate Profiles
  • Log D/Log P
  • pKa Determination
  • Physicochemical Characterization
  • Excipient Compatibility
  • Particle Characterization by:
    • Dynamic Light Scattering
    • Laser Diffraction
    • Zeta Potential
  • Differential Scanning Calorimetry with Modulated DSC Capabilities

Comprehensive Formulation Services

  • Parenteral Dosage Forms
  • Lyophilization Cycle Development
  • Emulsions/Suspensions
  • Drug Encapsulation in Liposomes and Microspheres
  • Admixture and Container/Closure Compatibility Studies
  • Manufacturability Assessments
  • Pilot Batch Production and Stability Analysis
  • Toxicology Supply Manufacturing/ Dosing Solutions

Disciplined Technology Transfer

Procedures and Processes

  • Batch Record Development
  • Method Transfer, Development and Validation
  • Scale-up Studies

YOUR PRODUCT. OUR EXPERTISE.


©2012 Avrio Biopharmaceuticals, LLC

4 Chrysler Irvine, CA 92618          866-98-AVRIO